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The questions arose because people with these diseases, which include rheumatoid arthritis (RA), psoriatic arthritis, axial spondylitis, lupus, and vasculitis, were specifically excluded from the clinical trials. Researchers offered the first signs of reassurance when they presented a real-world study, published in May 2021 in Annals of the Rheumatic Diseases, of the experience in Israel, which followed nearly 700 people with these diseases. The data were shared on June 5 at the virtual conference of EULAR, the European Alliance of Associations for Rheumatology....

Most Older Adults Diagnosed With Severe Depression Also Had Arthritis Researchers observed data collected from 2,438 women and 2,309 men over age 50 from a 2011 to 2014 National Health and Nutrition Examination Survey. Those surveyed were screened for depressive symptoms and self-reported doctor-diagnosed arthritis. The study showed that 55 percent of those experiencing minor depression also had an arthritis diagnosis, while 62.9 percent of people with moderate depression and 67....

The research, published this week in the Canadian Medical Association Journal by scientists from China, Taiwan, and Australia, showed an association between regular use of metformin and about a 30 percent reduced likelihood of needing total knee replacement or total hip replacement. This association did not mean that metformin was conclusively proven to cause a lower rate of joint replacements, according to study authors. Joint replacements are a common treatment for people with advanced osteoarthritis, a chronic joint disorder that often leaves older people in pain and unable to walk or perform other daily functions....

Semaglutide, sold under the brand names Ozempic and Rybelsus, helped most people with obesity in a clinical trial lose at least 10 percent of their body weight, and more than half of them reduced their weight by at least 15 percent, according to the study results, which were published in February 2021 in the New England Journal of Medicine. The study focused on a once-weekly injection of semaglutide at a higher dose than is approved for treatment of type 2 diabetes....

A study published in January 2020 in Mayo Clinic Proceedings supports other data that show having diabetes can take a serious toll on the heart. Indeed, the CDC notes that those with diabetes are twice as likely to die of heart disease as those without diabetes. Even after ruling out risk factors like high body mass index (BMI) and high blood pressure, diabetes significantly increases the likelihood of future heart failure, the new study found....

While a few lab and animal studies have shown promise, research on whether apple cider vinegar has a therapeutic effect on cancer in humans is lacking. What Is Apple Cider Vinegar? Apple cider vinegar is a type of vinegar that’s made of apples fermented with yeast and bacteria. It has a strong, sour taste and smell. Apple cider vinegar contains an acid called acetic acid. The acetic acid is what some people think may have an effect on cancer....

“One of the benefits of juicing is getting a concentration of vegetables into people who normally wouldn’t get enough,” says Sonya Angelone, RDN, a spokesperson for the Academy of Nutrition and Dietetics. But that doesn’t mean chugging glasses of your average fruit juice. There’s a right way — and a wrong way — to juice, Angelone says. Juicing When You Have Arthritis Foods can have an effect on inflammation in the body, which is related to arthritis....

Now two new studies suggest that it’s worth the effort even if you don’t hit the targeted amounts of these foods. In these studies — one focused on fruits and veggies and the other focused on grains — getting more of these foods was associated with a lower risk of developing type 2 diabetes. “We know diet is one of the most important factors that determine the risk of developing type 2 diabetes,” says Qi Sun, MD, a doctor of science and the senior author of the study that examined whole grains and a researcher at the Harvard T....

While most people try to avoid hurting others — and will feel guilty, remorseful, and distressed if they do hurt someone intentionally or unintentionally — an everyday sadist enjoys being cruel and may find it exciting. “We have probably all encountered people in our daily lives who — at least seem to — enjoy hurting others,” said lead researcher Erin Buckels, MA, who conducted this work as part of her master’s thesis in Social-Personality Psychology at the University of British Columbia....

Typically, bone pain is the first sign that cancer has spread to the bone. In some cases, however, bone metastases cause little or no symptoms, and it takes a routine scan or fracture from a minor fall or injury to uncover the bone cancer. “A fracture is one of the worst case scenarios, and one we try to avoid,” says Dr. Huston. While these secondary cancers in the bone are difficult to cure, many new and advanced treatments are available to lessen the symptoms and lengthen a person’s life....

The 12-week study included 78 men ranging from 50 to 70 years old with low or normal testosterone levels and no history of cardiovascular disease who could commit to a supervised workout program with aerobic and strength training two to three days a week. Researchers randomly assigned men to one of four groups: testosterone supplements with or without supervised workouts, or placebo supplements with or without the exercise program. At the start and end of the study period, researchers measured artery function using a method that increases blood flow inside an artery to whether the inner lining of the artery is healthy and can help the artery to increase in size or dilate....

“What happens when you deprive your body of carbohydrates is your body uses the fat as energy,” says Abby Langer, RD, Toronto-based founder of Abby Langer Nutrition. Eating this much fat produces ketone bodies and leads to ketosis, which means the body looks to fat rather than carbohydrates for fuel. What’s the benefit? For a lot of people, it’s all about weight loss. “Generally, [the keto diet] ends up being low-calorie,” Langer says....

The injected drug — so new it’s labeled SLN360 and has not yet been named — works by deactivating the gene responsible for lipoprotein(a) production. Patients who received higher doses of this drug saw their lipoprotein(a) levels drop by as much as 98 percent, according to preliminary trial results published April 3 in the Journal of the American Medical Association (JAMA). Five months later, these patients still had lipoprotein(a) levels 71 to 81 percent lower than before they received the drug....

That is perhaps why interest in mind-body therapies and wellness practices has skyrocketed in the past couple of decades. Now, nearly one-fifth of adults report engaging in a mind-body healing practice, according to recent research. Somatic movement practices like yoga, tai chi, and qigong, as well as mind-based disciplines like meditation, are becoming more commonly used to support improved well-being. In addition to these, the Feldenkrais Method, another somatic and mind-body practice, has emerged with rising interest in the wellness community....

In particular, Crohn’s disease can cause complications in a woman’s genital area or urinary tract. Because these issues can impact her reproductive and mental health, they require gynecologists and gastroenterologists to work together, according to a study published in October 2013 in the International Journal of Women’s Health. “There’s a huge overlap of symptoms [between Crohn’s and gynecological issues],” says Nirupama N. Bonthala, MD, a gastroenterologist who is part of the Integrated IBD Pregnancy and Fertility Program at Cedars-Sinai in Los Angeles....

AGE: 39 TITLE AND COMPANY: CEO, Medisafe After graduating from the University of Haifa and getting a graduate degree at the College of Management Academic Studies (the Collman) in Rishon LeZion, Israel, Omri Shor had a big idea. He was going to build a company that dealt in boat rentals. It would be called Marina123.com, and “the idea was to try and make renting a yacht as easy as 123,” says Shor, now 39....

Please join me, @EatSmartBD, along with @EverydayHealth by following #HealthTalk on Twitter on Thursday, March 14, 1-2 PM EST. You’ll get all of your burning diet and nutrition questions answered, and you’ll learn what you need to know to feed yourself and those you love with foods that fill you up without filling you out. March is National Nutrition Month — let’s spread the word about how easy it is to fuel your body and mind so you can feel your best every day....

From your own research or that of others, what have you learned about stress that you didn’t know or that surprised you? It has amazed me to learn that 20 percent of the population has a type of stress sensitivity that makes them more susceptible to the negative effects of stress. This sensitivity is genetically based and causes some people to be more influenced by the highs and lows of life....

The three common types of viral hepatitis — A, B, and C — are different. Hepatitis A does not require treatment and will clear up on its own in a few weeks or months. But hepatitis B or C, may develop into a chronic, long-term infection and can spread to sexual partners. Hepatitis can be spread by contact with infected body fluids such as: BloodSerumSemenVaginal fluid Sexual spread of hepatitis can occur through sexual intercourse and through other types of sexual contact that involve exposure to infected body fluids....

Because HAE is so rare, many doctors aren’t familiar with the disease. Also, your symptoms can mimic those of other conditions, which further complicates the process. To receive an HAE diagnosis, you’ll need to have a physical exam as well as blood tests, according to DiscoverHAE.com. (1) Making a HAE Diagnosis: Standard Blood Tests If your doctor thinks you might have HAE, he or she will probably first ask about your symptoms and family history....